Effects of not taking antiviral drugs for HCV positive individuals.

PATRICK N,Jan 16,2021

Hepatitis C is a disease caused by a type of virus which attaches liver and cause inflammation. It can be acute as it can lead to chronic as long as due to immunity or taking treatments and follow up well. It is transmitted through body fluids especially blood of a positive individual, by contact or by needle or other sharp objects or by other ways which can allow blood contact. For some time depending on the viral load, the breast feed and mother to children can allow contact.

when you get contact to this virus, no peripheral blood multiplication has found prior to liver cells. The target organ first is the liver and then in blood stream after multiplication. It is in this case that when a person is immune for, they can clear and cells evade this virus. Yet, for immunocompromised person, the virus increase in number and lead to enlargement of liver due to much increase of function to clear virus and too much sequestration.

A person diagnosed of any viral hepatitis especially Hepatitis C as it has no vaccine, should be followed up and take proper treatment well. It has some community education and screening that some when tested positive don’t step forward to approaching the in person institution to take treatment and this will not bring the virus infection to an end.

Because the liver plays such a pivotal role in the health of the body, when HCV impairs liver function, there can be a range of complications outside of the liver. 1 In one study, 38% of subjects with chronic HCV infection had at least one complication outside the liver. Skin (dermatologic) complications were common, affecting 17% of people and musculoskeletal complications (joint and muscle pain) occurred in 19% of people.

Several hematologic (blood) disorders are associated with HCV infection. One is cryoglobulinemia, in which the blood contains abnormal proteins called cryoglobulins. These proteins can thicken and clump together in blood vessels. Cryoglobulinemia can affect skin, muscles, joints, nerves, liver and kidneys. Joint pain, kidney disease, nerve problems, and purport (purplish skin discoloration) are common signs and symptoms of cryoglobulinemia.

HCV infection is also associated with conditions called monoclonal gammopathies, where there is an abnormal increase in B lymphocytes (a type of white blood cell) resulting in abnormally high amounts of immunoglobulin (antibody) production. HCV infection can also result in development of several different types of lymphomas, cancers of the lymph system.

HCV infection is associated with increased production of autoantibodies, antibodies that the body produces against its own tissues. A number of autoimmune disorders are associated with HCV infection.

The reason is that the viral quantities increase in blood and in other body fluid in addition to harming the targeted organ to the level that it shift from acute to chronic where liver is severely affected. Like this the probability of infecting the partners and other household whom sharing sharps materials occurs and the infectivity in community progress.

The community need education treatment than anything else because through community education the people can be aware and able to cope with the risk factors of different diseases. This can be done in different ways like mass education ,however to cope with corona virus prevention and control means, other ways such as radio, newspapers, burners, market radios, parking radio, and even one person one family education will be implemented and hope by educating one member in family to education that family would be much more educative and very cheap.

Taking the dose as prescribed by the doctor would with no doubt limit the replication and complications.

written by Patrick NEMEYIMANA /Reviewed on 16 jan 2021

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